The Prado and Reina Sofia Museums are around a 25-minute walk from the hotel, and Retiro Park is 1 kilometer away. The Colón Plaza is 400 meters away. By automobile, you can get to the Bernabéu Football Stadium and Milla de Oro in about 5 minutes. By bus, the Prado Museum and the Thysen Museum are about 7 minutes distant. Guests can order airport transfers for an additional fee.

Hotel Orfila's rooms are spacious and decorated in an attractive classic style with antique furnishings. There is a TV and a minibar in each room.

El Jardin de Orfila, the hotel's restaurant, is run by Michelin-starred chef Mario Sandoval and provides a variety of Mediterranean and regional dishes. A broad variety of local and international delicacies can be enjoyed in the luxurious on-site restaurant. The Orfila's patio and gardens are accessible from the tea room.

Meeting and conference rooms are among the other amenities available.

Wi-Fi is available throughout the property. You can store your valuables in the safe. Parking is available nearby. The friendly staff at the 24-hour front desk will be glad to answer your questions. Room service is also provided. There is a laundry at the hotel.